In the decider, Berrettini broke twice for a 4-2 lead but a rejuvenated Monfils dug deep and raced around the court to fight off three match points to force a final-set tiebreak. But it was Berrettini who leaned on his powerful serve to prevail and become the fourth Italian man to reach a Grand Slam semi-final in the Open Era.
Emma Raducanu did not drop a set since arriving at Flushing Meadows and won over the rowdy crowds at the Billie Jean King National Tennis Center as she swatted aside more experienced opponents with the same ease as she hammered winners.
Venus Williams kept up with little sister Serena on Wednesday, beating 78th-ranked Timea Bacsinszky of Switzerland in straight sets to advance to the third round of the US Open.
Serena Williams was the runner-up in Flushing Meadows each of the past two years
Alexis Olympia Ohanian donned braids with white beads on them, just as her mother Serena did when she first won the US Open as a teenager in 1999.
Venus Williams rejected the suggestion she might be content to serve as an inspiration to younger players after her 6-1, 0-6, 7-5 defeat to fellow American Sloane Stephens in the semi-finals.
Sharapova was granted a wildcard entry to the last Grand Slam of the season but received a tough first-round draw in the shape of Romanian Halep.
The win burnished Murray's reputation as one of the world's leading doubles exponents,
Juan Sebastian Cabal and Robert Farah became the first Colombians to win the US Open men's doubles title.
World number one Karolina Pliskova needed just 46 minutes to defeat American Jennifer Brady 6-1, 6-0 at Arthur Ashe Stadium and punch her ticket to the quarter-finals at the US Open on Monday.
Maria Sharapova has shrugged off Caroline Wozniacki's criticism of US Open organisers for giving the Russian centre court billing in her return to Grand Slam tennis after a doping ban.
Fourth seed Alexander Zverev will play Brandon Nakashima as the former finalist looks to end his long wait for a maiden Grand Slam title.
Images from the US Open women's singles second round matches, at Flushing Meadows, New York, on Thursday.
Images from Day 6 of the US Open in New York, on Saturday.
US Open Tournament Referee Soeren Friemel said there was "no other option" but to disqualify world number one Novak Djokovic on Sunday after he struck a line judge with a ball.
The US Open women's final between Emma Raducanu and Leylah Fernandez attracted a bigger audience on ESPN than the men's clash featuring calendar year Grand Slam-chasing Novak Djokovic and Russia's Daniil Medvedev.
A clash of generations will decide the US Open on Saturday with Serena Williams taking a fourth crack at Grand Slam history against teenager Bianca Andreescu, who was not even born when the American lifted her first Flushing Meadows trophy.
Novak Djokovic said he was "sad and empty" after a being disqualified from the US Open on Sunday after hitting a line judge in the throat with a ball during his fourth-round match against Spain's Pablo Carreno Busta.
American Rajeev Ram and Britain's Joe Salisbury beat Wesley Koolhof and Neal Skupski 7-6(4), 7-5 on Friday to become only the second pair to retain the US Open men's doubles title.
Images from Day 8 of the 2021 US Open in New York on Monday.
The first teenager to play in a US Open final since Serena in 2001 there was symmetry to the moment as Gauff rallied to beat the second seeded Belarusian 2-6, 6-3, 6-2 and end a six-year barren stretch for American tennis fans, who were finally able to celebrate a homegrown champion.
A crowd favourite for her creative playing style, Ons Jabeur rolls into her second straight Grand Slam championship match brimming with confidence, with lessons learned from her heartbreaking loss at the All England Club to Kazakhstan's Elena Rybakina.
Novak Djokovic took a first unsteady step toward completing the calendar-year Grand Slam on Tuesday as the Serb laboured into the second round of the US Open with a 6-1, 6-7(5), 6-2, 6-1 win over dashing Danish teenager Holger Rune.
Images from Day 1 of the 2022 US Open at the USTA Billie Jean King National Tennis Center, in Flushing Meadows, New York, on Monday.
Maria Sharapova's contentious and captivating US Open run came to an end on Sunday when Latvia's Anastasija Sevastova beat her 5-7, 6-4, 6-2 to reach the Flushing Meadows quarter-finals.
Images from the US Open women's singles quarter-finals at Flushing Meadows on Wednesday.
The 190th-ranked Indian stretched 20-time Grand Slam Champion Roger Federer to four sets in opening round of the US Open.
A summary of Friday's action at the US Open.
A summary of Sunday's action at the US Open.
The German sixth seed, who has not won a title since winning at Flushing Meadows last year, never got into the match against the 2016 WTA newcomer of the year.
Frances Tiafoe said his days of flying under the radar were over
'But I'm sitting out for the people, for my Aussies, for the hundreds and thousands of Americans that have lost their lives, for all of you. It's my decision.'
Ukrainian fourth seed Elina Svitolina powered into the third round of the U.S. Open with a 6-4, 6-4 win against Russian Evgeniya Rodina on Thursday.
Images from the US Open women's singles final at Flushing Meadows, New York, on Saturday.
'You cannot imagine, one player is going to die and then they're going to see'
IMAGES from Day 8 of the action at the US Open at USTA Billie Jean King National Tennis Center at Flushing Meadows in New York on Monday.
Roger Federer battled back from two sets down and double match point to defeat 20th seed Gael Monfils 4-6, 3-6, 6-4, 7-5, 6-2 to reach the semi-finals of the U.S. Open on Thursday.
The victory secured a first Grand Slam doubles championship for Laura Siegemund and a third for Vera Zvonareva
Naomi Osaka now gets to test her mental strength against a revitalised Victoria Azarenka, who stunned Serena Williams in Thursday's other blockbuster semi-final.
A summary of Thursday's action at the US Open.
